AbstractScience is based on the professional creation and certification of knowledge which is tied to powerful interest groups, notably the state, corporations and the scientific profession itself. Patriarchy is based on male control of dominant social structures and the exclusion of women from poisitions of power through means such as direct discrimination, socialisation and the gender division of labour.Patriarchy within the scientific community is manifested through male control of elite positions and various exclusionary devices. The scientific method incorporates masculine features such as the objectification of nature. Scientific knowledge is masculine in its neglect of women’s experience and its adoption of paradigms built on assumptions of competition and hierarchy.Four model strategies are analysed for challenging masculine science and building alternatives. Each of these strategies has strengths and limitations. Between them there may be hope for denting masculine-science-as-usual.