Isolation and evaluation of target cells in glaucoma research: Hormone receptors and drug responses
作者:
PolanskyJon R.,
AlvaradoJorge A.,
期刊:
Current Eye Research
(Taylor Available online 1985)
卷期:
Volume 4,
issue 3
页码: 267-279
ISSN:0271-3683
年代: 1985
DOI:10.3109/02713688509000858
出版商: Taylor&Francis
数据来源: Taylor
摘要:
To investigate the actions of drugs and hormones which influence intraocular pressure (IOP), we have been measuring receptor binding characteristics and dose-response effects using individual target cells from the anterior segment. Similar methods have also permitted us to develop sensitive radio-receptor assays for glucocorticoids and beta adrenergic antagonists. These methods provide a means to obtain new and potentially useful information regarding the efficacy and specificity of ocular drug therapy.
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