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Tests for Variation over Groups in Survival Data

 

作者: RobertJ. Gray,  

 

期刊: Journal of the American Statistical Association  (Taylor Available online 1995)
卷期: Volume 90, issue 429  

页码: 198-203

 

ISSN:0162-1459

 

年代: 1995

 

DOI:10.1080/01621459.1995.10476502

 

出版商: Taylor & Francis Group

 

关键词: Censored failure time data;Correlated data;Counting processes;Proportional hazards

 

数据来源: Taylor

 

摘要:

When survival data can be divided into natural groups, such as in a clinical trial with patients from a number of different institutions, the question arises whether effects are different for the different groups. For situations where one is concerned with a random pattern of variation over groups, this article proposes testing the null hypothesis of no variation using statistics based on the sums of martingale residuals over subjects within groups. These tests are closely related to the locally most powerful tests of Liang for testing for variation across a large number of strata. The tests are applied to data from a lung cancer trial conducted by the Eastern Cooperative Oncology Group.

 

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