Age-related changes in the molecular properties of vitreous collagen
作者:
AkibaJun,
UenoNorio,
ChakrabartiBireswar,
期刊:
Current Eye Research
(Taylor Available online 1993)
卷期:
Volume 12,
issue 10
页码: 951-954
ISSN:0271-3683
年代: 1993
DOI:10.3109/02713689309020402
出版商: Taylor&Francis
数据来源: Taylor
摘要:
To understand the molecular events underlying rheological vitreous changes, age-related changes in the molecular properties of bovine and human vitreous collagen were monitored by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The adult bovine vitreous showed an increase in the highmolecular-weight components of the collagen compared with the young samples. In addition, the apparent molecular size of theα-chain of the adult type II collagen was slightly larger than that of the young samples. The same tendency also was observed in human vitreous. The increase of high-molecular-weight components of the vitreous collagen could be attributed to intermolecular cross-links of the peptide chains.
点击下载:
PDF (418KB)
返 回