AbstractWe studied 65 insulin‐dependent diabetic children and adolescents diagonosed during the period 1976–86 to find out the occurrence and duration of postini‐tial remission, the relationship between the remission behaviour and the initial treatment introduced by continuous subcutaneous insulin infusion (CSII), the favoring factors and the prognostic value of remission. A postinitial remission occurred in 36 patients (55.4%) being complete in only two boys (3.1%). The mean duration was 10.8 months and median was 7.8 months: the shortest period one month and the longest 36 months. On the other hand, remission occurred in 16 out of 19 patients (84.2%) with CSII and 15 out of 37 patients (40.5%) with conventional treatment (CT) as initial treatment. The mean duration of remission was 14.6 ± 10.6 months in the CSII group and 6.8 ± 4.7 months in the CT group. Further, our study proved a significant increase of urinary C‐peptide excretion in the patients with CSII during their remission. Through our study in comparison with CT, we were able to see an improvement in the remission rate by introducing the CSII for a short term in the initial treatment and it led us to realize that what caused it was the recovery of endogeneous insulin secretion