Serum Protein Polymorphisms in a Liberian Population
作者:
M. Willcox,
G. Beckman,
L. Beckman,
期刊:
Human Heredity
(Karger Available online 1986)
卷期:
Volume 36,
issue 1
页码: 54-57
ISSN:0001-5652
年代: 1986
DOI:10.1159/000153601
出版商: S. Karger AG
关键词: Polymorphism;Haptoglobin;Gc groups;Transferrin;α1-Antitrypsin;Liberia
数据来源: Karger
摘要:
Serum protein variations were studied in a Liberian population living in Buchanan town. Of the α1-antitrypsin genes only M1and M3 were polymorphic. The frequencies of the haptoglobin and Gc genes were in accordance with earlier known estimates in African populations. There was, however, a relatively low frequency of Hp 0 which may be related to the low malarial parasite prevalence in this group. The transferrin C2 gene was found in a significantly lower frequency among Liberians compared to European and Asiatic populations. A new transferrin variant was observed by isoelectric focusing. This variant could not be identified with conventional starch or polyacrylamide electrophoresis
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