首页   按字顺浏览 期刊浏览 卷期浏览 Use of Interleukin‐2 in Patients with Acquired Immunodeficiency Syndrome
Use of Interleukin‐2 in Patients with Acquired Immunodeficiency Syndrome

 

作者: Clifford Lane,   Jay Siegel,   Alain Rook,   Henry Masur,   Edward Gelmann,   Gerald Quinnan,   Anthony Fauci,  

 

期刊: Journal of Biological Response Modifiers  （OVID Available online 1984）
卷期: Volume 3, issue 5  

页码: 512-516

 

ISSN:0732-6580

 

年代: 1984

 

出版商: OVID

 

关键词: Acquired immunodeficiency syndrome;Immunomodulation;Interleukin‐2;In vivoimmune status;Toxicity.

 

数据来源: OVID

 

摘要:

Summary:Twelve patients with acquired immunodeficiency syndrome were treated with a natural product, highly purified human interleukin‐2. Doses ranged from 250 to 250,000 units. No clinical responses were seen. Minimal toxicity was noted and consisted of mild prolongation of partial thromboplastin time and proteinuria. Immunologic changes during the study included a decrease in the number of circulating T8 lymphocytes, increased skin test reactivity, and a decline in serum immunoglobulin levels.

 

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