Acinar Cell Carcinoma of Rat Pancreas
作者:
Kalipatnapu N. Rao,
Hishashi Shinozuka,
期刊:
Digestion
(Karger Available online 1984)
卷期:
Volume 29,
issue 1
页码: 31-36
ISSN:0012-2823
年代: 1984
DOI:10.1159/000199005
出版商: S. Karger AG
关键词: Rat;Pancreatic cancer;Glycoproteins;Glycosidases
数据来源: Karger
摘要:
Cancer cells in culture, and their corresponding nude mouse transplantable tumors, derived from azaserine-induced rat pancreatic acinar cell carcinomas showed a shift from high to low molecular weight glycoproteins when compared with normal, fetal, and regenerating pancreas. A 51,000-dalton glycoprotein was present only in the transplantable nude mouse tumors. Cancer cells and transplantable tumors showed elevated levels of glycosidases, and the former showed higher activities than the latter. Some of the glycosidase activities in host pancreas and liver were elevated.
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