Thyroxine-Binding Globulin in Spontaneous Abortion
作者:
Lottie Skjöldebrand,
Jan Brundin,
Anders Carlström,
Tom Pettersson,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1986)
卷期:
Volume 21,
issue 4
页码: 187-192
ISSN:0378-7346
年代: 1986
DOI:10.1159/000298952
出版商: S. Karger AG
关键词: Spontaneous abortion;Thyroid profile
数据来源: Karger
摘要:
Thyroxine-binding globulin (TBG), thyroxine-binding prealbumin (TBPA), thy-roxine (T4), free T4, triiodothyronine (T3) and thyroid-stimulating hormone (TSH) were studied in 144 apparently healthy, euthyroid pregnant women displaying miscarriages. In an additional group of 18 aborting women a frozen blood sample drawn in early pregnancy was similarly analyzed for the thyroid components as well as for human chorionic gonadotropin (HCG). The values were compared to those of normal pregnancies (n = 228) at corresponding intervals. Significantly lower values of TBG were found in the spontaneously aborting women. Slightly lower values were found concerning T4 and T3 in the spontaneously aborting group. A significantly lower value of TBG was found to be more predictive concerning spontaneous abortion than that of HCG.
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