A Selective Pharmaceutical Analysis Technique with Sensitive Piezoelectric Crystal Quartz Sensors
作者:
Wei Wanzhi,
Hu Changwen,
Zhu Wenhong,
Yao Shouzhuo,
期刊:
Analytical Letters
(Taylor Available online 1993)
卷期:
Volume 26,
issue 11
页码: 2371-2383
ISSN:0003-2719
年代: 1993
DOI:10.1080/00032719308017477
出版商: Taylor & Francis Group
关键词: piezoelectric sensor;conductivity;hydrolysis;atropine
数据来源: Taylor
摘要:
The frequency shift of a piezoelectric crystal sensor showed a linear dependence on the concentration for drugs which can be hydrolyzed in base aqueous solutions, at a given reacting time after the addition of the base, when the base concentration is basically constant during the entire measurement period. The sensitivity of the analysis method was improved, if crystal responses at different reacting times were recorded and utilized to estimate component concentration, when used for determining atropine sulfate in a pharmaceutical compound. The analytical results indicated that the selective and sensitive analytical procedure could be easily applied in true low concentration pharmaceutical analysis.
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