Renal Microangiopathy in the Primary Antiphospholipid Syndrome: A Case Report with Literature Review
作者:
Somnuek Domrongkitchaiporn,
Eugene C. Cameron,
Nazma Jetha,
Barry O. Kassen,
Roger A.L Sutton,
期刊:
Nephron
(Karger Available online 1994)
卷期:
Volume 68,
issue 1
页码: 128-132
ISSN:1660-8151
年代: 1994
DOI:10.1159/000188231
出版商: S. Karger AG
关键词: Antiphospholipid syndrome;Renal microangiopathy;Acute renal failure
数据来源: Karger
摘要:
We report the case of a 52-year-old male patient with recurrent thrombosis from ‘primary antiphospholipid syndrome’ who developed renal microangiopathy. Despite anticoagulant therapy with coumadin, serum creatinine progressively increased from 398 to 592 μmol/l and platelets decreased to 43,000. The patient responded to high-dose methylprednisolone and aspirin and the renal function improved. A review of the literature disclosed 4 other cases of association between primary antiphospholipid syndrome and renal microangiopathy. The clinical characteristics of these cases are discu
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