Lipids as modulators of bone remodelling
作者:
Bruce Watkins,
Yong Li,
Mark Seifert,
期刊:
Current Opinion in Clinical Nutrition and Metabolic Care
(OVID Available online 2001)
卷期:
Volume 4,
issue 2
页码: 105-110
ISSN:1363-1950
年代: 2001
出版商: OVID
数据来源: OVID
摘要:
Bone remodelling processes are regulated by systemic hormones and a multitude of local and systemic factors, including prostaglandins, cytokines, and growth factors. Dietary fatty acids and their derivatives (eicosanoids) have been a recent focus of investigation on bone and cartilage metabolism. Specific fatty acids are recognized modulators of eicosanoid biosynthesis, signal transduction, and gene expression. The actions of polyunsaturated fatty acids have not been extensively examined in the skeletal system. Promising research on fatty acids and bone remodelling should evaluate the potential effects on pathways for osteoclastogenesis and osteoblastogenesis.
点击下载:
PDF
(88KB)
返 回