Second-Derivative Spectrophotometric Determination of Some Benzenoid Drugs
作者:
M.M. Abdel-khalek,
M.E. Abdel-hamid,
M.S. Mahrous,
M.A. Abdel-salam,
期刊:
Analytical Letters
(Taylor Available online 1985)
卷期:
Volume 18,
issue 7
页码: 781-792
ISSN:0003-2719
年代: 1985
DOI:10.1080/00032718508066176
出版商: Taylor & Francis Group
关键词: benzenoid drugs;second-derivative spectrophotometry;pharmaceutical formulations
数据来源: Taylor
摘要:
A rapid second-derivative spectrophotometric assay procedure has been described for the determination of some benzenoid drugs in pharmaceutical dosage forms. Spectral interference from formulation excipients in simple uv spectrophotometric methods has been eliminated by the application of the proposed method. The different assay parameters, linearity and precision of the method have been assessed. The assay results obtained for eight batches of the pharmaceutical formulations of these drugs are in accord with the declared amounts. The high specificity, ease and simplicity offered by second-derivative spectrophotometry permit unit dose assay of these formulations.
点击下载:
PDF (388KB)
返 回