ABSTRACT: Results of computer calculations are presented which predict the pressure response of a closed casing annulus of an injection well to temperature and pressure variations of the injected waste stream. For example, a 3000 ft. disposal well receiving fluid at 100d̀F might cause an increase in annular pressure of some 500 psi. Graphs summarizing these results are included. The results will be of interest to waste injection well operators, inasmuch as they are required to monitor annulus pressure to prove mechanical integrity of their injection wells