Separation of Two Hepatitis B Human Antibody Fractions by Cold‐Ethanol Precipitation
作者:
Marilyn S. Horowitz,
Kenneth R. Woods,
Merril Gersten,
Carlos Ehrich,
期刊:
Vox Sanguinis
(WILEY Available online 1976)
卷期:
Volume 30,
issue 1
页码: 50-57
ISSN:0042-9007
年代: 1976
DOI:10.1111/j.1423-0410.1976.tb04833.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Abstract.Antibodies to three different samples of hepatitis B antigen‐positive serum were found to be absent from a Cohn fraction II hepatitis B immune globulin preparation, but present in the whole plasma from which the immune globulin was made. Fractions containing the antibodies specific for the three antigen samples were isolated from the plasma by euglobulin precipitation, and the antibodies were characterized as to immunoglobulin class and precipitability in the Cohn fractionation procedure. They appear to be IgG antibodies which, however, were detectable only in Cohn fraction I, while the remainder of the HB specificity present in the original plasma was found, as expected, in fraction I
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