Possible Overestimation of Plasma Volume Determined by the Indocyanine Green Dilution Method in the Presence of Protein Leak From Capillary Beds – A Discussion of Two Clinical Cases
作者:
H. Ishihara,
H. Ohkawa,
T. Iwakawa,
K. Takamura,
T. Tsubo,
A. Matsuki,
期刊:
Transfusion Medicine and Hemotherapy
(Karger Available online 1997)
卷期:
Volume 24,
issue 1
页码: 10-13
ISSN:1660-3796
年代: 1997
DOI:10.1159/000223453
出版商: S. Karger GmbH
关键词: Indocyanine green;Plasma proteins;Plasma volume measurement;Complications (pulmonary edema, burn)
数据来源: Karger
摘要:
Indocyanine green (ICG) has been demonstrated to be a reliable indicator for the estimation of plasma volume in man. Since this dye is bound to plasma protein when administered intravenously, overestimation of the plasma volume would occur during the presence of protein leak from plasma. However, to our knowledge, up to now no report has described whether or not plasma volume determined by the indocyanine green dilution method (PVICG) is clinically significantly overestimated under such conditions. We report two burned patients who temporally had an unusual large PVICG even though other clinical variables did not support the presence of hypervolemia. From the case described it can be concluded that a possible overestimation of PVICG occurs when the vascular permeability for proteins is increased.
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