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OESOPHAGEAL CANCER: OUTCOME OF MODERN SURGICAL MANAGEMENT

 

作者: I. O'Rourke,   N. Tait,   C. Bull,   V. Gebski,   M. Holland,   D. C. Johnson,  

 

期刊: Australian and New Zealand Journal of Surgery  (WILEY Available online 1995)
卷期: Volume 65, issue 1  

页码: 11-16

 

ISSN:0004-8682

 

年代: 1995

 

DOI:10.1111/j.1445-2197.1995.tb01739.x

 

出版商: Blackwell Publishing Ltd

 

关键词: adenocarcinoma;carcinoma;dysphagia;oesophageal;oesophagus;squamous cell carcinoma.

 

数据来源: WILEY

 

摘要:

Many clinicians still associate oesophagectomy for oesophageal carcinoma with low cure rates, poor palliation and prohibitive peri‐operative mortality. Surgical advances have rendered such perceptions inaccurate. A prospective study of all patients undergoing surgery for oesophageal cancer in an Australian teaching hospital between 1979 and 1993 has been undertaken. Selection. staging, pre‐operative preparation, surgical technique and postoperative care were all carefully controlled. One hundred and thirty‐seven patients were explored. Twenty‐one were inoperable. One hundred and sixteen underwent resection with intent to cure. Hospital mortality for oesophagectomy was 1.7%. There were no cases of clinical anastomotic leakage. Eighty‐nine per cent achieved excellent to good swallowing. The median survival for all cases was 14 months and the 5 year survival was 18%. Median survival for resected cases was 18 months and the 5 year survival was 26%. The long‐term survival was related to postoperative stage of the disease but not to tumour type. Oesophagectomy for oesophageal cancer will restore good swallowing in 90% of cases. Operative mortality should be less than 5% and the overall 5 year survival 20–3096. Early tumours can often be cured (ca in situ100%. stages I and II 50–60%), indicating the benefits of early detection. Poor survival in advanced disease (stage III 15%. stage IV 0%) on a background of low surgical mortality indicate the need for better staging and more effective adj

 

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