THE TREATMENT OF HIRSUTISM: EXPERIENCE WITH CYPROTERONE ACETATE AND SPIRONOLACTONE
作者:
A. K. Thomas,
R. Slobodniuk,
J. Taft,
M. Cooper,
J. Montalto,
G. Jerums,
期刊:
Australasian Journal of Dermatology
(WILEY Available online 1985)
卷期:
Volume 26,
issue 1
页码: 19-24
ISSN:0004-8380
年代: 1985
DOI:10.1111/j.1440-0960.1985.tb01809.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SUMMARYTwenty‐three patients were treated with either cyproterone acetate (n = 14) or spirono‐ lactone (n = 12) for a period of not less than twelve months. Plasma and urinary androgen levels fall significantly with cyproterone acetate but showed little change with spironolactone. Sebum production fell in both groups as did hair diameters. The frequency of cosmetic measures used by the patients was reduced during both forms of therapy. No serious side effects were observed. However, these drugs should not be used in patients without adequate contraception because of the risk to the foetus. Further evaluation of the relative merits of the two drugs is requi
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