Short‐term prophylaxis with cefotaxime in colorectal surgeryA prospective, randomized trial
作者:
F. Lauridsen,
K. Bjoernsen,
S. Damgaard Nielsen,
Hart Hansen,
期刊:
Diseases of the Colon & Rectum
(OVID Available online 1988)
卷期:
Volume 31,
issue 1
页码: 25-27
ISSN:0012-3706
年代: 1988
出版商: OVID
关键词: Surgery, colorectal;Penicillin;Streptomycin;Cefotaxime;Wound infection
数据来源: OVID
摘要:
&NA;In a controlled, randomized study the effect of penicillin and streptomycin on postoperative septic complications in colorectal surgery (penicillin, 2 ml, IU, intramuscularly, three times daily for a period of six days and concomitantly streptomycin, 0.5 gm, intramuscularly, two times daily for a period of four days) was compared with the effect of cefotaxime, 2 gm, intravenously, three times on the day of surgery. One hundred patients completed the study: 48 were treated with penicillin and streptomycin (Group 1) and 52 with cefotaxime (Group 2). Wound infection occurred in one patient (2.1 percent) in Group 1, but not in Group 2 (0%, N.S.). Rupture of the wound occurred in one patient in each group (2.1 percentvs. 1.9 percent, N.S.). Insufficiency of the anastomosis occurred in four patients in Group 1 (8.3 percent) and in one patient in Group 2 (1.9 percent). It is concluded that short‐term prophylaxis with cefotaxime is as effective as long‐term prophylaxis with penicillin and streptomycin.
点击下载:
PDF
(239KB)
返 回