Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter→q15
作者:
S. Minoshima,
M. Amagai,
J. Kudoh,
R. Fukuyama,
T. Hashimoto,
T. Nishikawa,
N. Shimizu,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1991)
卷期:
Volume 57,
issue 1
页码: 30-32
ISSN:1424-8581
年代: 1991
DOI:10.1159/000133108
出版商: S. Karger AG
数据来源: Karger
摘要:
Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p– (6pter→q15::16q24→qter). The gene (BPA230) was located to the chromosome region 6pte
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