Stereocontrolled Conversion of Allylic Alcohols Into VicinalCis-Diols: New Syntheses of Methyl α-L-Digitoxoslde and Methyl 2-Deoxy-α-L-Fucoside
作者:
HenryW. Pauls,
Bert Fraser-reid,
期刊:
Journal of Carbohydrate Chemistry
(Taylor Available online 1985)
卷期:
Volume 4,
issue 1
页码: 1-14
ISSN:0732-8303
年代: 1985
DOI:10.1080/07328308508062945
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A synthetic process is outlined in which an allylic alcohol is converted into its primary urethane derivative, which is then subjected to iodonium ion induced cyclization to give a single iodo-carbonate. The carbonate is then deiodinated reductively and hydrolyzed to afford the vicinal diol. By use of this process the two title sugars have been prepared from methyl 2.3.6-trideoxv-α-L-ervthro-hex-2-enopvranoside and its α-L-threo counterpart.
点击下载:
PDF (608KB)
返 回