Male rats were orally administered an inhibitor of angiotensin‐converting enzyme (ACE), N‐[(S)‐1 ‐(ethoxycarbonyl)‐3‐phenylpropyl] ‐1 ‐ala‐1 ‐pro maleate (enalapril, MK‐0421) at dosage levels of 10, 30, and 90 mg/kg·d. After 2–6 wk of dosing, the rats receiving 30 and 90 mg/kg·d produced large numbers of seminal plugs and had lacerated penises due to licking in an attempt to recover urine. Providing 0.9% saline as the source of drinking water prevented this behavior and subsequent lesions. There were no adverse effects on reproductive performance. A subsequent study showed that enalapril at 5 mg/kg·d po and captopril (another ACE inhibitor) at 25 mg/kg·d po increased NaCI intake in rats. Our results with captopril confirm those of Fregly (1980) and Evered and Robinson (1983) and show that both converting‐enzyme inhibitors (enalapril and captopril) increase salt appetite in rats.