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DISCRIMINATION BETWEEN HLA‐DR1 (DRB1*0101) AND DR'Br’(DRB1*0103) USING SEQUENCE‐SPECIFIC OLIGONUCLEOTIDE PROBES

 

作者: J.L. Bidwell,   E.A. Bidwell,  

 

期刊: International Journal of Immunogenetics  (WILEY Available online 1991)
卷期: Volume 18, issue 1‐2  

页码: 105-109

 

ISSN:1744-3121

 

年代: 1991

 

DOI:10.1111/j.1744-313X.1991.tb00010.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

SUMMARYSerological identification of the HLA‐DQw1(w5)‐associated or HLA‐DQw3(w7)‐associated DR ‘Br’(DRB1*0103) allele cannot be accomplished in the presence of a second DQw1(w5)‐positive or DQw3(w7)‐positive haplotype, respectively. DNA‐restriction fragment length polymorphism (RFLP) analysis assists in identification of DR ‘Br’, though not in the presence of DR1. We describe an alternative or complementary method for identification of DR ‘Br’ using two oligonucleotide probes which target

 

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