Effect of menthol on the bladder cooling reflex in the cat
作者:
S. LINDSTRÖM,
L. MAZIÈRES,
期刊:
Acta Physiologica Scandinavica
(WILEY Available online 1991)
卷期:
Volume 141,
issue 1
页码: 1-10
ISSN:0001-6772
年代: 1991
DOI:10.1111/j.1748-1716.1991.tb09037.x
出版商: Blackwell Publishing Ltd
关键词: autonomic reflex;cold receptors;menthol;urinary bladder
数据来源: WILEY
摘要:
The effect of menthol on the urinary bladder cooling reflex was studied in α‐chloralose‐anaesthetized cats. The cooling reflex was elicited by bladder or urethral instillations of cold saline and monitored by multiunit recordings from efferent and afferent pelvic nerve filaments. The bladder cooling reflex was greatly exaggerated by intraluminal exposure of the bladder or the urethra to a 0.6 mmsolution of menthol. The effect occurred without a sensitizing effect on bladder mechanoreceptors. It could be described as a shift of the temperature‐response curve for the cooling reflex towards higher temperatures. This change resembles the effect of menthol on cutaneous cold receptors. It is proposed that the bladder cooling reflex originates from cold receptors in the bladder and urethral
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