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Lignans fromKadsura angustifolia

 

作者: Ye-Gao Chen,   Guo-Wei Qin,   Yu-Yuan Xie,   Kin-Fai Cheng,   Zhong-Wen Lin,   Han-Dong Sun,   Young-Hwa Kang,   Byung-Hoon Han,  

 

期刊: Journal of Asian Natural Products Research  （Taylor Available online 1998）
卷期: Volume 1, issue 2  

页码: 125-131

 

ISSN:1028-6020

 

年代: 1998

 

DOI:10.1080/10286029808039854

 

出版商: Taylor & Francis Group

 

关键词: Lignan;Kadsura angustifolia;Anti-PAF activities

 

数据来源: Taylor

 

摘要:

A new dibenzocyclooctadiene lignan named angustifolin D (1) together with four known lignans: kadsulignan L (2), kadsulignan N (3), schisantherin P (4) and meso-dihydroguaiaretic acid (5) were isolated from the stems ofKadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies. Compounds2and5showed moderate plateletactivating factor (PAF) antagonistic activities with IC50values of 2.6 × 10−5and 4.1 × 10−5M, respectively.

 

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