Properdin Factor B Polymorphism in Four Sardinian Villages
作者:
I. Borelli,
E. Olivetti,
N. Cappello,
S. Rendine,
E.S. Curtoni,
期刊:
Human Heredity
(Karger Available online 1987)
卷期:
Volume 37,
issue 4
页码: 217-221
ISSN:0001-5652
年代: 1987
DOI:10.1159/000153706
出版商: S. Karger AG
关键词: Bf polymorphism;Population study;Italy;Sardinia
数据来源: Karger
摘要:
A sample of healthy unrelated individuals was typed for properdin factor B (Bf) polymorphism in four Sardinian villages. Two villages, Desulo and Tonara, are located in the highlands; the other two, Orosei and Galtelli, are located in the lowlands. No heterogeneity was found between the highland and the lowland villages, whereas a significant difference was found between the Sardinian villages and continental Italy. The allele Bf-F1 shows the highest gene frequency so far observed. Typically Sardinian is the gametic association (haplotype) HLA-A30, Cw5, B18, BfF1, DR3.
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