Human gene mapping by postreduction and recombination frequencies under complete interference
作者:
Jurg Ott,
期刊:
Clinical Genetics
(WILEY Available online 1979)
卷期:
Volume 15,
issue 1
页码: 11-16
ISSN:0009-9163
年代: 1979
DOI:10.1111/j.1399-0004.1979.tb02023.x
出版商: Blackwell Publishing Ltd
关键词: Gene mapping;ovarian carcinoma;postreduction;recombination.
数据来源: WILEY
摘要:
Gene‐centromere distances can be estimated (i) by determining postreduction frequencies by means of ovarian teratomas and (ii) by analysis of genetic linkage between a gene locus and a structural chromosome polymorphism near the centromere. The two methods are compared under complete interference. It is shown that the teratoma method is at least twice as efficient as the recombination method. Two estimates of the map distance for a combination of both data types are derive
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