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In Vivo Voltammetric Determination of Neurotransmitters with Simply Activated and Modified Carbon Fiber Electrodes

 

作者: Tuzhi Peng,   Guoshun Wang,   Huiping Li,   Baoen Shen,   Guoqing Liu,   Yuping Cao,  

 

期刊: Analytical Letters  （Taylor Available online 1995）
卷期: Volume 28, issue 3  

页码: 395-403

 

ISSN:0003-2719

 

年代: 1995

 

DOI:10.1080/00032719508001105

 

出版商: Taylor & Francis Group

 

关键词: In-vivo voltammetry;Chemically modified electrode;Electrochemical treatment;Neurotransmitter

 

数据来源: Taylor

 

摘要:

This paper describes a simple procedure for treating carbon fiber electrodes. After constant potential activation and electrostatic dip modification, the electrode shows high sensitivity and selectivity for in-vivo determination of neurotransmitters. The modified electrode is only responsive to primary monoamines (DA and 5-HT) and insensitive to AA, UA and anionic metabolites. The selectivity of the electrode has been demonstrated by local microinjection and pharmacologic manipulation.

 

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