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A simplified method for large‐scale HPA‐la phenotyping for antenatal screening

 

作者: P. Metcalfe,   H. A. Doughty,   M. F. Murphy,   A. H. Waters,  

 

期刊: Transfusion Medicine  （WILEY Available online 1994）
卷期: Volume 4, issue 1  

页码: 21-24

 

ISSN:0958-7578

 

年代: 1994

 

DOI:10.1111/j.1365-3148.1994.tb00239.x

 

出版商: Blackwell Publishing Ltd

 

关键词: alloimmune thrombocytopenia;antenatal screening;HPA‐la;MAIPA

 

数据来源: WILEY

 

摘要:

SUMMARY.A simplified method for large‐scale HPA‐la phenotyping of platelets was developed for use in an antenatal screening programme for fetomaternal alloimmune thrombocytopenia (FMAIT). The test was based on the MAIPA assay, which was modified for antigen‐typing with a well‐characterized anti HPA‐la reagent. The resulting assay gave reliable results, was inexpensive and allowed testing of large batches using semiautomated

 

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