Sustained Antidepressive Effect of Repeated Partial Sleep Deprivation
作者:
Edith Holsboer-Trachsler,
Klaus Ernst,
期刊:
Psychopathology
(Karger Available online 1986)
卷期:
Volume 19,
issue 2
页码: 172-176
ISSN:0254-4962
年代: 1986
DOI:10.1159/000285151
出版商: S. Karger AG
数据来源: Karger
摘要:
In a naturalistic clinical trial we administered three partial sleep deprivations (PSD) within one week to a diagnostically heterogeneous sample of 30 depressed patients and applied serially three dexamethasone suppression tests (DST). We observed that this PSD treatment induced sustained clinical improvement independently from nosological attribution. Abnormal DST results prior to PSD treatment failed to predict clinical course, and normalized after beneficial response.
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