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Zur Wirkung von 8-Methoxypsoralen (8-MOP) und Blacklight auf Mikroorganismenin vitround den Ablauf der experimentellen Meerschweinchen-Trichophytie

 

作者: H. Oberste-Lehn,   M. Plempel,  

 

期刊: Dermatology  （Karger Available online 1977）
卷期: Volume 154, issue 4  

页码: 193-202

 

ISSN:1018-8665

 

年代: 1977

 

DOI:10.1159/000251066

 

出版商: S. Karger AG

 

关键词: 8-Methoxypsoralen;Antimicrobial activity;Therapeutic effects in experimental dermatomycosis

 

数据来源: Karger

 

摘要:

The lack of experimental test models causes problems in comparative evaluations of photodynamic effects of 8-MOP and its possible derivatives after irradiation with blacklight or other irradiation sources. In our experiments in vitro, tests with various microorganisms and the in vivo model of experimental dermatophytosis in guinea pigs by Trichophyton mentagrophytes appeared to be suitable. In vivo, 8-MOP was applicated orally and topically in two formulations.

 

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