Tuberculosis in Cancer PatientsAn Update
作者:
Herman Libshitz,
Harpreet Pannu,
Linda Elting,
Catherine Cooksley,
期刊:
Journal of Thoracic Imaging
(OVID Available online 1997)
卷期:
Volume 12,
issue 1
页码: 41-46
ISSN:0883-5993
年代: 1997
出版商: OVID
关键词: Tuberculosis;Tuberculosis, demographics;Malignancy, complications
数据来源: OVID
摘要:
The demographics of tuberculosis (TB) and the therapy of malignancies have significantly changed since the last comprehensive review of TB in cancer patients. Fifty-six patients with both TB and malignancy were identified from January 1989 through December 1994 in a population of 61,931 newly registered cancer patients. The frequency of TB in cancer patients was 90 per 100,000. TB was more frequent in foreign-born patients (p< 0.001) and in racial and ethnic minorities (p< 0.001) than in non-Hispanic whites. TB developed during therapy in 48%. TB was discovered synchronously with the malignancy in 30% and in 21% occurred ≥18 months after therapy. Pulmonary TB occurred in 50 (89%) patients and extrapulmonary TB in nine (16%) (three had both). Chest radiographic findings did not suggest TB in 20%. TB was less frequent in lung cancer (p< 0.001), head and neck cancer (p= 0.002), and solid hematologic malignancies (p< 0.001) than it had been historically, but the frequency was unchanged in acute leukemia patients (p = 0.46). TB in cancer patients occurs at a nine times greater frequency than in the general population. It is now most frequent in leukemia patients.
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