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Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4‐cacetylsulphamethoxazole in the snail Cepaea hortensis

 

作者: TomB. Vree,   MonikaL. Vree,   JacquesF. M. Nouws,  

 

期刊: Veterinary Quarterly  （Taylor Available online 1987）
卷期: Volume 9, issue 4  

页码: 378-381

 

ISSN:0165-2176

 

年代: 1987

 

DOI:10.1080/01652176.1987.9694129

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

The snail Cepaea hortensis is able to acetylate and hydroxylate sulphamethoxazole in a similar way to man. About one percent deacetylation, but no hydroxylation of N4‐acetysulphamethoxazole takes place. The relative rates of the metabolic pathways for hydroxylation and acetylation of sulphamethoxazole are equal.

 

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