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Voltammetric Behaviour of Ketorolac and Its HPLC-EC Determination in Tablets.

 

作者: J.A. Squella,   I. Lemus,   J.C. Sturm,   L.J. Núñez-Vergara,  

 

期刊: Analytical Letters  （Taylor Available online 1997）
卷期: Volume 30, issue 3  

页码: 553-564

 

ISSN:0003-2719

 

年代: 1997

 

DOI:10.1080/00032719708001801

 

出版商: Taylor & Francis Group

 

关键词: Voltammetry;HPLC;Electrochemical Detection;Ketorolac.

 

数据来源: Taylor

 

摘要:

Ketorolac is an antiinflammatory-analgesic agent that is oxidizable at the glassy carbon electrode. The voltammetric oxidation produces two well resolved pH-dependent peaks, that are overlapped at pH>10. Using this voltammetric response a HPLC procedure with electrochemical detection in order to quantify ketorolac in pharmaceutical dosage forms is presented. Furthermore comparative methods using UV spectrophotometry and HPLC with photodiode array detector were used.

 

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