The Mechanism of Action of Digitalis
作者:
LangerGlenn A.,
期刊:
Hospital Practice
(Taylor Available online 1970)
卷期:
Volume 5,
issue 8
页码: 49-57
ISSN:2154-8331
年代: 1970
DOI:10.1080/21548331.1970.11705897
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The ability of digitalis to potentiate cardiac contraction is intimately related to its interference with the active transport mechanism involved in the translocation of sodium and potassium across the cell membrane. This is also the mechanism that explains the toxicity problems so often encountered with use of the cardiac glycosides—myocardial irritability and heart block.
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