Cell Growth Simulation (CGS): the design philosophy
作者:
SERAJY. ABED,
OSMANS. OZKUL,
MUSTAFAM. AL-IDRISI,
SUFIAN EL-ASSOULI,
MAJID AMER,
期刊:
International Journal of Systems Science
(Taylor Available online 1993)
卷期:
Volume 24,
issue 12
页码: 2219-2227
ISSN:0020-7721
年代: 1993
DOI:10.1080/00207729308949624
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Cell Growth Simulation (CGS) is a software package that simulates the growth of cell cultures, and the effects of different types of agents on the cell populationsin vitro. It is a stochastic simulation system based on the cell cycle kinetics. Experiments involving DNA synthesis blocking, mitosis inhibition, labelling and cell kill can be simulated by imitating agents such as thymidine, aphidicoline, hydroxyurea, vincristine, vinblistine, colcemid and others. The model to be simulated is described by the user according to his theoretical convictions, The system provides numerous facilities to help the user describe an experiment and examine the simulation results. A menu driven interactive scheme is used to communicate with the user. CGS has a modular structure and its general structure, design philosophy and capabilities are presented. The system has been developed through the cooperation of industrial engineering, cell biology, medical oncology and computer programming disciplines. It is implemented on PCs with hard disks and 512K bytes of RAM using the True Basic language.
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