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Evaluation of Systemic and Splanchnic Visceral Oxygen Variables in Dogs With Surgically Induced Gastric Dilatation‐Volvulus

 

作者: J. Komtebedde,   W.G. Gullford,   S.C. Haskins,   J.R. Snyder,  

 

期刊: Journal of Veterinary Emergency and Critical Care  (WILEY Available online 1991)
卷期: Volume 1, issue 1  

页码: 5-13

 

ISSN:1479-3261

 

年代: 1991

 

DOI:10.1111/j.1476-4431.1991.tb00088.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

SummaryGastric dilatation‐volvulus (GDV>was surgically induced in ten dogs to evaluate changes in the following variables: surface oxygen partial pressure (PsO2) of splanchnic viscera, systemic O2transport (DO2), systemic O2consumption (VO2), and O2utillization ratio (O2UR). These variables have been shown to be closely correlated to tissue viability and patient survival in a variety of ischemic disorders.Gastric dilatation‐volvulus was corrected after 2.5 hours and the dogs were given lactated Ringer's solution (90ml/kg) over 30 minutes (resuscitation). At 6 hours, the dogs were euthanized without recovery from anesthesia.Gastric dilatation‐volvulus resulted in a significant (p<0.05) decrease of splanchnic visceral PsO2and DO2and a significant (p<0.01) increase in O2UR. Systemic O2consumption did not change significantly during the experiment.Resuscitation resulted in a translent and significant (p<0.05) increase in PsO2to baseline, except for hepatic PsO2. Systemic O2transport and O2UR increased significantly (p<0.001) compared to baseline. Surface oxygen partial pressure and D02were significantly (P<0.05) below baseline at the conclusion of the experiment, whereas O2UR remained significantly (p<0.05) above baseline. Surface oxygen partial pressure of all splanchnic viscera, except liver PsO2correlated DO2throughout the experiment (r: 0.69–0.78).Assessment of DO2, VO2, and O2UR may be used to evaluate efficacy of cardiovascular support during corrective surgery for can

 

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