Hepatitis B Vaccination in Dialysis Patients and Nutritional Status
作者:
M. Lombardi,
F. Pizzarelli,
M. Righi,
T. Cerrai,
P. Dattolo,
S. Nigrelli,
S. Michelassi,
S. Sisca,
A. Alecci,
P. Di Geronimo,
Q. Maggiore,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 61,
issue 3
页码: 266-268
ISSN:1660-8151
年代: 1992
DOI:10.1159/000186900
出版商: S. Karger AG
关键词: Anti-HBV vaccination;Dialysis;Nutrition
数据来源: Karger
摘要:
35 dialysis patients underwent anti-HBV vaccination. We classified patients in responders or non-responders using an anti-HBs titer of 50 UI/l as the discriminating serum level and tried to assess whether the antibody response bears any relationship with the nutritional status. 26 patients (74%) reached the target atb titer, which was maintained during follow-up (average 360 UI/l). The weak response in the other 9, with values never exceeding 20 UI/l, was short-lived. Anthropometric and impedenziometric parameters were higher in responders than in nonresponders, but the difference did not reach statistical significance. We conclude that the atb titer which discriminates uremics in responders or not must be > 50 UI/l and that the nutritional status may interfere with the seroconversion rate, but this conclusion needs to be validated in a wider population.
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