Imaging of diffusion and microcirculation with gradient sensitization: Design, strategy, and significance
作者:
Denis Le Bihan,
Robert Turner,
Chrit T. W. Moonen,
James Pekar,
期刊:
Journal of Magnetic Resonance Imaging
(WILEY Available online 1991)
卷期:
Volume 1,
issue 1
页码: 7-28
ISSN:1053-1807
年代: 1991
DOI:10.1002/jmri.1880010103
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Blood, flow dynamics;Blood vessels, MR studies, 17.1214;Brain, MR studies, 10.1214;Brain, perfusion;Cerebral blood vessels, flow dynamics;Cerebral blood vessels, MR studies, 17.1214;Diffusion imaging;Echo‐planar imaging;Microcirculation imaging;Physics;Pu
数据来源: WILEY
摘要:
AbstractRecent developments in the use of magnetic resonance (MR) to measure and image diffusion and blood microcirculation (“perfusion”) are summarized. After a brief description of the effects of diffusion and perfusion on the MR signal, the different methods (conventional spin‐echo, stimulated‐echo, gradient‐echo, and echo‐planar imaging) that have been proposed and used to image and measure diffusion and perfusion by gradient sensitization are presented, along with their advantages and limitations. The difficulties of diffusion/ perfusion imaging related to both hardware and software are then discussed. Special attention is given to specific problems encountered with in vivo studies and data analysis. Finally, the potential biologic and clinical applications are outlined, and some examples ar
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