Screening for Spinal Defects
作者:
HaddowJames E.,
期刊:
Hospital Practice
(Taylor Available online 1982)
卷期:
Volume 17,
issue 1
页码: 128-138
ISSN:2154-8331
年代: 1982
DOI:10.1080/21548331.1982.11698027
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Second-trimester diagnosis of most open neural tube defects has become clinically feasible in the past five years. Alpha fetoprotein is the common denominator in a two-stage screening program. Maternal serum analysis identifies high-risk pregnancies; amniotic fluid analysis is diagnostic. The biochemical basis for these tests and findings of clinical studies are reviewed.
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