Spectrophotometric Determination of Diclofenac Sodium in Gel-Ointment
作者:
I. Kramancheva,
I. Dobrev,
L. Brakalov,
A. Andreeva,
期刊:
Analytical Letters
(Taylor Available online 1997)
卷期:
Volume 30,
issue 12
页码: 2235-2249
ISSN:0003-2719
年代: 1997
DOI:10.1080/00032719708001735
出版商: Taylor & Francis Group
关键词: Spectrophotometry;Diclofenac Sodium determination;Gel-Ointment
数据来源: Taylor
摘要:
A direct spectrophotometric method has been developed for quantitative determination of Diclofenac Sodium in gel-ointments. The reported technique does not require a separation step and it is based on only one extraction of Diclofenac Sodium from the gel-ointment and measurement of the absorbance at two wavelengths. This procedure allows also indirect quantitative determination of degradation products due to indolinone cyclization. The method is rapid, simple, specific, reproducible and stability indicating.
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