Growth and adult survival rates were estimated for the endangered Colorado squawfishPtychocheilus luciusinhabiting the upper Colorado River by using data from fish captured during 1990–1995. Mean annual growth rates of fish aged 3–6 years ranged from 32.2 (age 6) to 82.0 (age 3) mm/year. Growth rates for older fish were highest for fish 400–449 mm total length, TL, (42.7 mm/year) and declined to 19.8 mm/year for fish 500–549 mm TL. Fish 550 mm and longer grew an average 9.5 mm/year. Survival rates for fish 550 mm and longer were estimated by comparing measured size distributions with simulated stable age and size distributions; these ranged from 0.83–0.87, with the best fit at 0.85. Though lack of historical data precludes comparisons with past growth and survival rates, our data serve as a baseline for future population monitoring efforts.