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The Effect of Pentobarbital on Basal and Ether-Stimulated ACTH Secretion in Intact and Adrenalectomized Rats

 

作者: M.A. Greer,   Catherine F. Allen,  

 

期刊: Neuroendocrinology  (Karger Available online 1975)
卷期: Volume 17, issue 3  

页码: 258-264

 

ISSN:0028-3835

 

年代: 1975

 

DOI:10.1159/000122361

 

出版商: S. Karger AG

 

关键词: Ether;Pentobarbital;Adrenalectomy;Stress;ACTH

 

数据来源: Karger

 

摘要:

Pentobarbital in a dose of 3.5 mg/100 g b.w. did not suppress the high basal a.m. levels of plasma ACTH in adrenalectomized male rats. In both intact and adrenalectomized rats prior administration of the drug slightly depressed the rise in plasma ACTH induced by 2.5 min of ether inhalation, but this depression is of questionable statistical significance.

 

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