The Measurement of Muscle Mass in Children Using [15N]Creatine
作者:
DAVID PICOU,
P. REEDS,
A. JACKSON,
N. POULTER,
期刊:
Pediatric Research
(OVID Available online 1976)
卷期:
Volume 10,
issue 3
页码: 184-188
ISSN:0031-3998
年代: 1976
出版商: OVID
数据来源: OVID
摘要:
In eight infants and children who had recovered from proteinenergy malnutrition (PEM), muscle mass was estimated by measuring creatine turnover by an isotope dilution technique using [15N]creatine, creatine concentration, and urinary creatinine output. Creatine turnover varied from 1.5 to 2.6% of the muscle creatine pool per day and muscle creatine concentration ranged from 1.7 to 3.9 μg/μg muscle DNA. Muscle mass was between 15% and 37% of total body weight. The results indicate that daily creatinine output is not a reliable indicator of muscle mass in children who have recently recovered from severe PEM.
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