ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb10564.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTThe prevailing theory that normal intelligence and mild mental retardation are determined by multiple additive genes is critically reviewed in the light of findings from recent population studies. Discrepancies between theoretical concepts and reported data are noted, particularly those concerning frequency of mild mental retardation, sex ratio, and additional somatic and psychiatric handicaps in populations with mild mental retardation.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06218.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTAnalysis of previously published CSF monoamine data has revealed statistical evidence for a biological subtype of depression, characterized by abnormally low CSF‐5HIAA and CSF HVA. Using maximum likelihood gaussian mixture analysis we were able to resolve the empirical frequency distributions of both CSF HVA and CSF 5‐HIAA into two component normal mixtures. Simultaneous analysis of both CSF 5‐HIAA and CSF HVA revealed a two component bivariate normal mixture distribution in which 35% of the depressed patient sample were classified in the low subgroup. No evidence for mixture distributions was found in controls. Analysis of CSF MHPG revealed a single component normal distribution with virtually identical mean and variance in both patients and controls. These results are shown to be virtually identical to parallel analyses conducted on CSF monoamine data collected as part of the NIMH collaborative study on the psychobiology of depression

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06219.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTSixteen patients with senile dementia of the Alzheimer type (SDAT) were compared with 11 age‐matched normal subjects with respect to their responses of thyrotrophin (TSH) and prolactin (PRL) to thyrotrophin releasing hormone (TRH) challenge. Both groups showed a continuing rise in TSH response at 60 min, and no difference was found between the groups. A significantly exaggerated PRL response at 20 min was found in the SDAT group. There was no difference between sexes with respect to either the TSH or PRL response. These findings, albeit preliminary, may have implications for dopaminergic impairment in SDA

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06220.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTThe study comprises a consecutive evaluation of 88 first‐admission patients from a well‐defined catchment area. All patients disclosed functional delusional psychosis at PSE interview. Sex distribution was equal and the patients’ mean age in the thirties. Symptomatology and diagnostic classification are presented and, for the latter, related to the Catego Class of PSE. Forty‐five patients fulfilled Catego Class S+, the majority being diagnosed reactive psychosis while only 13 patients were diagnosed schizophrenia. At discharge, 44 patients were fully remitted. A follow‐up will be made of social and clinical course an

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06221.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTIn this study employed and unemployed male parasuicides were compared on a number of clinical, sociodemographic and other characteristics in order to establish which, if any, were significantly related to employment status. A further analysis examined variation in personal attributes by duration of unemployment. The unemployed group was found to contain a higher proportion of individuals who were unmarried, living outside the family, of lower social class, given a diagnosis of abnormal personality, misusing drugs habitually, in trouble with the police and with a criminal record. Comparisons within the unemployed group showed that age and civil state varied significantly by duration of unemployment, but no linear trend was evident. Longer durations of unemployment were associated significantly with personality diagnosis and receipt of psychotropic drug treatment. Within the limits dictated by the study design (cross‐sectional, without general population controls), the findings are discussed in terms of their compatibility with the causal or self‐selection models of the unemployment‐parasuicide relatio

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06222.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTAntenatal care consumption, obstetric conditions, and neonatal health, were studied retrospectively in all women in the county of Stockholm who had a baby during 1976–77 and also had been admitted to a psychiatric department after the 20th week of pregnancy or within the first postpartum year, and the findings were compared in matched obstetric controls. Fewer index women had had uncomplicated pregnancies than the controls. A positive relationship was found between acute mental illness and pregnancy complications. Delivery complications tended to to be more common in the index group than in controls, but, only in patients with prepartum onset of mental illness. More index women had a history of several previous abortions than the controls. The index women, and especially the addicts, attended the antenatal care clinics significantly less frequently than the controls. The neonatal health of the index children seemed to be more closely correlated with alcohol or drug dependencyper sein the mothers than with mental illnes

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06223.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTA group of 25 hospitalised schizophrenics who had attempted suicide within the past year was compared with another group of 30 hospitalised schizophrenics who had not attempted suicide, using the PSE symptoms. The former had a significantly higher number of symptoms indicative of a depressive disorder. It is concluded that suicidal risk in schizophrenia is significantly raised when there are concomitant depressive symptoms.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06224.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTFrom the Stockholm County in‐patient register we selected all patients with schizophrenia, discharged from all hospitals in the county during 1971, in voluntary and compulsory care. The cohort of 1190 patients was followed for 10 years in the national cause‐of‐death register. 231 deaths were identified and 68 came under the ICD chapter XVII, “Injuries…”. These 68 deaths were analysed through medical records and death certificates in order to find out detailed causes of death, evidence of misclassification, and information on suicides during psychiatric care. Of the 68 deaths 33 were classified as suicides, 14 undetermined, 20 accidents and one homicide. Suicides predominated among the younger patients and accidents among the elderly. By scrutinizing medical records we identified seven deaths we judged to be suicides but which had been classified as accidents or undetermined. 36% of all deaths and 44% of those classified as suicides occurred during psychiatric care. The record‐linkage method proved valuable for identifying deaths among psychiatric patients and for obtaining data on hospital care, thus giving access to medical records, and should be useful in fur

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06225.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

ABSTRACTAt a London hospital the prevalence and types of recorded paranoid disorders, and their characteristics were extracted from the files of in‐patients of various cultural groups. It was found that West Indians and Africans had more paranoid colouring in their psychiatric illness than any other group. Other immigrant groups had less paranoid features than the English group. The self or a family member was the commonest focus of intended harm in all the cultural groups. Supernatural modes of injury were common in the West Indians and Africans. It is argued that in immigrants paranoid disorder is not merely due to discrimination consequent on their migrant status, but that cultural factors inherent in the immigrants are also of etiological importanc

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1986.tb06226.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY