摘要:

Sixty patients who had a major psychiatric breakdown following stress were studied. The mode of presentation of one group led to the suspicion of a reactive psychosis and comparison with the other group showed that in terms of the actual or threatened loss of an emotionally significant person, the temporal relationship between stress and illness and the distribution of vulnerable personalities, there was a significant difference between the groups. The sex ratio and frequency distribution for age were also suggestive. In view of the above and the known clinical course of the illness and comparison with the work of major workers in this field, it seems reasonable to believe that grounds exist for accepting the diagnosis of reactive psychoses in Sri Lanka.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03558.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

An unusual case of presenile cortical atrophy is described wherein the presenting feature was pathological stealing. The extended course of the illness is discussed together with its diagnostic implications.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03559.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

On admission, IgA, IgG and IgM concentrations were determined in 76 schizophrenics, and the correlations of these concentrations to the variables relating to psychopathology, background and prognosis were investigated in the present study, which is a part of a more extensive unpublished study.On the basis of factorization, the highest IgM concentrations were found in withdrawn schizophrenics and the lowest in paranoid schizophrenics. Of the background variables, the patient's present age had a positive correlation and his place of birth (rural‐urban) a negative correlation to IgA concentrations, both being at a statistically significant level. IgA and IgM values higher than average at the beginning of treatment predicted a short hospital stay. Earlier, these patients had also needed little hospital care in relation to the duration of the disease.A hypothesis based on the results is presented, according to which a different way of reacting to stress may explain the differences in IgM concentrations in withdrawn and paranoid schizophrenics.The connection between prognosis and immunoglobulins was considered at least partially explainable on the grounds of age at the onset of the diseas

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03560.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

The therapeutic effect of lithium in Huntington's chorea was tested in six patients through a double‐blind cross‐over comparison of lithium and placebo, each administered for 6 weeks. Four of the patients received neuroleptic drugs at the same time.Lithium and placebo periods did not did not differ as regards motor skills, hyperkinesias, or total ward situation, all rated quantitatively with the use of scales. Lithium does not seem to be of therapeutic value in Huntington's cho

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03561.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

This paper reports a marked decrease in total hours of sleep in depressed and manic patients on days 3 and 4 following discontinuation of alpha‐methyl‐para‐tyrosine (AMPT), a specific inhibitor of the synthesis of the neurotransmitters, norepinephrine and dopamine. Discontinuation of two precursors of biogenic amines, L‐dopa and L‐tryptophan, produced no changes in total sleep. It is suggested that the decrease in sleep following AMPT may result from catecholamine neuronal receptor hypersensitivity induced during AMPT treatment. Animal data consistent with this hypothesis are reviewed. The importance of studying rebound phenomena following psychoactive drugs and the practical therapeutic implications of these findings are

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03562.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Five aspects of suicidal behaviour in Edinburgh from 1968 to 1974 were examined. The data referred to 478 suicidal deaths and to parasuicide (attempted suicide) admissions to the Regional Poisoning Treatment Centre (R.P.T.C.).Firstly: 28 % of suicides were found to have had a parasuicide admission and there was some evidence of a slight excess of deaths in the years immediately following parasuicide. Secondly: among suicides preceded by parasuicide, those with a recent episode (within 2 years of death) were found to be essentially similar to those with a longer interval. Thirdly: a history of previous parasuicide at any time was found to be important in delineating two groups of suicide. Suicides with prior parasuicide died more often from poisoning with drugs and were more likely to have a history of psychiatric treatment; suicideswithoutprior parasuicide died more often from poisoning with domestic gas or violent means, were older, of higher social class and less often married. Fourthly: parasuicides who killed themselves within 2 years of admission to the R.P.T.C. were compared with a group of (broadly nonsuicidal) parasuicides. And lastly: a scale predictive of repetition of parasuicidal behaviour was used in an attempt to distinguish parasuicides who killed themselves from those who did not. The scale did not discriminate between the two groups.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03563.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Twenty‐five children with radiologically confirmed primary peptic ulcers were investigated. All patients suffered from duodenal ulcer and there was an unexpected female preponderance. The frequency of introverted personalities was greater in the patients than in the controls. Five patients suffered from psychiatric disorders, three had histories of suicidal attempts and three reported homosexual experiences. Six patients had nicknames. Eight patients had been operated on for appendicitis. The above parameters were negative in all control cases. The patients had lower mean IQ, worse adaptation to school, more anxious and overprotective parents, higher frequency of faddiness in food and lower frequency of nail‐biting than the controls. The onset of symptoms was preceded by psychotraumatic events in eight cases.The findings suggest that the manifestation of the genetic background of duodenal ulcer is strongly influenced by environmental factors and factors associated with the personality of the patie

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03564.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

The antidepressive efficacy of TRH was investigated in 15 endogenous depressive patients in a double‐blind cross‐over design. The Hamilton depression scale, the AMP (PAS) system, v. Zerssen scale and thermometer scales were used. No therapeutic effect could be demonstrated. The blunted TSH‐response to TRH, which has been described by other investigators, was confirmed. There was suggestive evidence of a psychoendocrinological relationship in the sense that the more severe the “somatic depressive” syndrome as calculated from the AMP system, and the more marked the diurnal variation of the endogenous type is, the lower are the basal TSH values and the smaller the response to TRH. Thus, TRH may become a useful tool to identify subgroups of depressive patient po

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03565.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

An intraindividual double‐blind cross‐over comparison of the anterograde effect on memory of unilateral non‐dominant fronto frontal (FF) and temporo‐parietal (TF) ECT was performed in connection with the second and third treatment of an ECT‐series, the electrode placement being alternated at random. Treatment technique was standardized and seizure duration was measured by means of EEG. Memory functions were tested after treatments by means of four memory tests: the 30 Word‐Pair Test, the 30 Figure Test, the 30 Geometrical Figure Test and the 30 Face Test. Three operationally defined memory variables, immediate memory (IMS, 3 hours after ECT), delayed memory (DMS, 3 hours after IMS), and their difference, forgetting, were scored.No differences were found in the mean time of electrical stimulation, in the amount of methohexital and suxamethonium chloride, and in seizure duration between the two treatment groups. No statistically significant differences in any of the memory tests were found. The FF electrode position did not show any advantage compared with the routine TP electrod

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03566.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Book reviews in this article:Janz, D.: EpileptologyLaslett, R.: Educating maladjusted children.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1977.tb03567.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY