摘要:

120 schizophrenic patients, all first admissions to four different psychiatric units, were followed up for 4 years to assess their progress while their cases were managed largely extramurally and the patients lived mostly at home. They were found to spend little time in hospital, but only a few of them remained symtom‐free throughout the follow‐up period. In spite of that, a good many were able to work.The effect the patient has on the household to which he or she belongs is considerable in terms of loss of earnings, separations from children, frequent disturbing behaviour and so on. Nevertheless many families seem to be able to endure this without complaining unduly.They seem to be able to bear the burden easier if the psychiatric services are part of a general hospital rather than based on a mental hospi

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08215.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

For the purpose of investigating the effects of long‐term therapy with clopenthixol in terms of measurable laboratory parameters, 57 female patients who had been treated with clopenthixol alone from 3 to 9 years were examined. Twenty‐six patients had psychiatric diseases only 31 had concomitant somatic diseases. Several parametric and non‐parametric statistical methods (especially Spearman's Rho) were used to study the relationships between the measured values, in particular variations within the range between the two groups. Age, dose and duration of treatment were variables along with laboratory tests.There were no indications that long‐term treatment with clopenthixol exerts a nephrotoxic, hepatotoxic, or haematotoxic effect. Changes did seem to occur in certain parameters, predominantly within the range of normal, especially as concerns thymol turbidity values and total leucocyt

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08216.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

This is the third in a series of investigations of social effectiveness defined by educational and occupational achievement among patients with primary affective disorder. As in previous studies, there is no evidence that patients with primary affective disorder differ significantly in social achievement from their own siblings. This study in an attempt to replicate achievement from their own siblings. This study is an attempt to replicate previous findings that bipolar patients and their family members have higher levels of social achievement than unipolar patients and their family members. The results of this study confirm previous results among publically hospitalized patients when they have a history of previous private hospitalization. The hypothesis that a social advantage is associated with bipolar primary affective disorder is not supported by data from publically hospitalized patients without a history of previous private hospitalization. The possible reasons for these findings are discussed, as well as the type of study wich would be required to resolve the questions raised by the present investigation.

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08217.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

The assumption that oral diazepam treatment (20 mg daily) during 5 days in combination with active in‐patient crisis intervention has a favourable effect on acute clinical anxiety states was examined. A simple double‐blind random placebo‐diazepam design was applied on 30 crisis‐patients. The clinical improvement is defined as a difference‐score in ratings based on psychiatric interviews and ward observation.The evidence derived from totals of Hamilton scales, nurse scales, and visual analogue scales does not support the assumption that diazepam is therapeutically better than placebo if one compares the two medication groups as units. But for the sub‐group of patients with the highest levels of pre‐treatment anxiety, a short‐term administration of oral diazepam seems to be a valuable adjunct to a crisis intervention program. Moreover, diazepam has a selective action for the improvement of insomnia, respiratory and gastro‐intestinal complaints. Finally, diazepam or some factor connected with it has an adverse influence on some autonomous complaints.The need for the study of the relationship between clinical effect and pharmacokinetic values, especially plasma concentrations of the drug and its active metabolite is sugge

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08218.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

In this study, a group of depressed patients who did not attempt suicide was compared with a group of depressed patients who attemptd suicide. All were English females. The two groups were comparable with regards to social class, and marital status. The suicidal group was younger.The results show no significant difference between the two groups in the degree of severity of depression, which was assessed using the Hamilton Depression Rating Scale. However, there was a significant difference in the degree of social dysfunction between the two groups. This was assessed using the Social Dysfunction Rating Scale described by Linn and co‐author

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08219.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Twenty‐one female schizophrenics (age range 34–74 years) were included in a clinical study assessing the effectiveness of penfluridol as a basic maintenance therapy. At the start of the study, the patients, all of whom had been successfully maintained on penfluridol for at least 6 months, were divided into two comparable groups. Group I (ten patients) received penfluridol and Group II(II patients) placebo under double‐blind conditions for 6 months. Patients were evaluated using a 36‐item questionnaire, which was completed before and after 1, 3, 4 and 6 months of treatment.When at any time during the study a patient deteriorated, haloperidol in individually adjusted doses was added to her treatment regimen. By the end of the study, eight of the 11 placebo patients received additional haloperidol, whereas only three of the penfluridol patients did.Evaluation of the scores on the rating scale showed no significant differences between the two treatment groups. The trial confirmed previously gained experience that penfluridol is a very suitable drug for the maintenance therapy of chronic schizophrenic p

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08220.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

The mortality of all patients seen at the Department of Psychiatry, the General Hospital in Lund, Sweden during 1962 was studied for the years 1962–1968. The number of deaths was 260. The expected number of deaths in a corresponding sample of the general population was 159. The mortality was significantly increased in both men and women. The ratio between observed and expected mortality was highest in the younger age groups. The overmortality was due mainly to an increased number of suicides, accidents and nervous and circulatory diseases in the men and suicide and cancer in women.The patients who died were compared with a randomized subsample of psychiatric patients sill alive at the end of the observation time. The items chosen for comparison were social and medical factors previously found to be related to mortality. The purpose was to try to recognize high risk groups within the psychiatric population.Divorced persons were more common among those who died than among controls, and more males who died were living along, unemployed or invalid pensioners. Mortality seemed to be independent of type of care in 1962 in terms of hospitalization and out‐patient contact. Differences found in psychiatric services by those who had died and controls before and after 1962 were of low significance. The one outstanding psychiatric diagnosis among those who died was the organic brain syndrome. Alcoholism was more common among men who died accidental deaths compared with controls.More than 50% of the patients who committed suicide had previously attempted suicide. A high proportion of those who died were hospitalized in somatic wards and sent to the psychiatric out‐patient department for psychiatric assessment. Common reasons for referral were recently attempted suicide and pain, often of unknown o

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08221.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Book Reviewed in this article:Zubin, J.,&J. Money (eds.): Contemporary sexual behavior.Gross M. M. (Ed): Alcohol intoxication and withdrawal. Experimental studies. Advances in experimental medicine and biology, Vol. 35Meyer, J.‐E.: Tod und Neurose.Heppner, F.: Limbisches System und Epilepsie. Aktuelle Probleme in der Psychiatrie, Neurologic, Neurochirurgi

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08222.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0001-690X    

DOI:10.1111/j.1600-0447.1974.tb08223.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY