ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb05158.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb05159.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb15568.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb04642.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

摘要:

SummaryThe neurological syndrome in the present series is found to be in good agreement with that described in classical Friedreich's ataxia.1. Sense impairment is, however, more common than in some other series, and electroneurography discloses disturbed function of both motor and sensory nerves.2. The kyphoscoliosis is graded. Minor spinal anomalies are detected at roentgenological examination in some cases.3. Diabetes mellitus with an average age at onset of 22 years is present in 11 of the 56 patients. Abnormal glucose tolerance is demonstrated in an additional 3 cases.4. Serum transaminases are normal in the 29 cases in which they are determined.5. No increase in the urinary excretion of catechol amines is recorded.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb04643.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb05146.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

摘要:

SummaryThe cardiomyopathy of Friedreich's ataxia is not associated with any characteristic symptoms and signs. However, ahnormal sound phenomena from the heart occur, and have been studied by phonocardiography.1. More than one‐third of the probands were earlier suspected to have congenital heart disease, on the grounds of a murmur. In 6 patients, the murmur later evidently disappeared completely.2. Phonocardiographic recordings show a systolic murmur of ejection type, with a maximum over the 2nd left interspace in 14 of 39 patients. The murmur is of higher frequency and amplitude, and begins later in systole, than is usual m a physiological murmur.3. Anatomical and haemodynamic features may be responsible for the murmur.4. A significantly higher incidence of murmur is found in the younger patients. A decreased stroke volume is suggested to explain the disappearance of the murmur in older patients.5. A split second sound with an interval of more than 4 csec is present in about half of the cases. A probably significant correlation exists between abnormal splitting of the second sound and the occurrence of a systolic murmur of grade 2–4.6. Accentuated, high‐frequent third and fourth sounds, causing gallop rhythm, are present in 8

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb04644.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

摘要:

It was reported that, a t the control carried out (i months after discharge, 9 % of all the patients had sequelar of their head injuries. Pour cases coilsistcd of patients who exhibited neuro‐ logical symptoms; only 9 of these rases. however, could be regarded as sequelae. Otherwise, slight psychiatric symp: o 2 s of an uncharacteristic type were stated Lo have oecurred. In all these cast,:, nervous symptoms had appeared previously in the history, or the children lived apparently undcr chronic stress. Of the fit3 patients. who had formerly been free from psychic symptoms and lived under ordinary home conditions, none displayed pychiatric symptoms after sustaining a head injury. It was not possiblc to show any connection between the degee of severity of the head injtiries and the occurrence of sequela

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb04635.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb15569.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1964.tb15570.x

出版商:Blackwell Publishing Ltd    

年代:1964

数据来源: WILEY