摘要:

Abstract.Eriksson, B. O. (Department of Paediatrics, University of Göteborg, Göteborg, Sweden). Muscle metabolism in children—a review. Acta Paediatr Scand, Suppl. 283: 20, 1980.—The muscle tissue is by far the most energy demanding organ in the body. Studies on energy liberation and muscle substrate levels in normal and sick children can give an important contribution to the knowledge and understanding of the problems in each disorder. Muscle metabolic data are presented from infants with symptomatic ventricular septal defect (VSD), children with coarctation of the aorta, children with coeliac disease and with late walking debute. The difference in muscle substrate levels and muscle enzyme activities in normal children 2 months to 15 years of age are also presented, as well as the effect of exercise and physical tra

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb15304.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Yetgin, S., Gur, A. and Saatci, U. (Department of Paediatrics, Children's Medical Center, Hacettepe University, Ankara, Turkey). Non‐specific immunity in nephrotic syndrome. Acta Paediatr Scand, 69:21, 1980.—In order to explain susceptibility to bacterial infection in patients with nephrotic syndrome, bactericidal capacity of polymorphonuclear neutrophils (PMN) and serum opsonic activity were studied. The groups consisted of 29 patients and 29 controls. Bactericidal capacity was found to be statistically significant defective in the patient group when compared with controls forStaphylococcus aureusandEscherichia coli. Serum opsinic activity was found to be defective in up to 50% of the patients, but it was not statistically significant for either bacteria. There is no correlation between the impairment of bactericidal capacity and serum total protein, albumin, globulin, total lipid, cholesterol, age of patients and the duration of the illness. When bactericidal capacity was examined in five patients in remission it had returned to the normal level. The results of this study suggest that bactericidal capacity and possibly serum opsonic activity are influenced by the nephrotic synd

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb07023.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb06221.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb06222.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Chandra, R. K.&Kutty, K. M. (Department of Pediatrics, Memorial University of Newfoundland, St. John's, Newfoundland, Canada). Immunocompetence in obesity. Acta Paediatr Scand 69:25, 1980.—Thirty‐eight % of obese children and adolescents showed a variable impairment of cell‐mediated immune responsesin vivoandin vitroand reduction of intracellular bacterial killing by polymorphonuclear leukocytes. The obese group had a higher incidence of iron deficiency and moderately lower serum zinc concentrations. Levels of serum immunoglobulins, complement components C3 and C4, and numbers of T and B lymphocytes were comparable in the two groups. Serum triglycerides, cholesterol and lipoproteins were normal in all subjects. Immunologic changes correlated with the presence of subclinical deficiencies of iron and zinc. Therapy with these micronutrients for 4 weeks resulted in improvement in immunologic res

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb07024.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb15305.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb06215.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Thorén, C. (Department of Pediatrics, St. Göran's Children's Hospital, Stockholm, Sweden). Exercise testing with special reference to children with diabetes mellitus. Acta Paediatr Sand, Suppl. 283: 29, 1980.—The purpose of exercise testing in diabetes mellitus is to examine physical fitness and to motivate the patient to perform physical activity as a valuable part of the treatment. Different types of tests and ergometry are presented. The step wise increase of workload at submaximal levels is recommended for diabetics as an annual test. Maximal exercise is of value in determining the maximal oxygen uptake (v˙o2max)=the aerobic capacity, maximal heart rate and systolic blood pres

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb15306.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Brodersen, R., Lakatos, L. and Karmazsin, L. (Institute of Medical Biochemistry, University of Aarhus, Denmark, and Pediatric Clinic, University Medical School, Debrecen, Hungary). D‐penicillamine, a non‐bilirubin‐displacing drug in neonatal jaundice. Acta Paediatr Scand, 69:31, 1980.—D‐penicillamine, a drug used clinically for the treatment of neonatal hyperbilirubinaemia, was tested for interference with the binding of bilirubin to human serum albumin by three methods: 1) The peroxidase technique, investigating the effect of D‐penicillamine on the equilibrium concentration of unbound bilirubin in a solution containing a molar excess of albumin; 2) the MADDS method, measuring the concentration of vacant bilirubin binding site on albumin in a solution of pure albumin, or infant blood serum, with added D‐penicillamine; and 3) injection of D‐penicillamine into Gunn rats and determination of any decrease of plasma biiirubin which would be caused by displacement of the pigment. Results were negative in all cases. Quantitatively, the doses of D‐penicillamine used clinically cannot displace bilirubin from its binding to albumin. The ameliorating effect on hyperbilirubinaemia in the newborn must be due to so

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb07025.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1980.tb06223.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY