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1. |
ANDERS SPARRMAN AND HIS TRANSLATION OF ROSÉN VON ROSENSTEIN'S TEXTBOOK ON CHILDREN'S DISEASES DURING CAPTAIN COOK'S EXPEDITION TO THE ANTARCTIC REGIONS AND ROUND THE WORLD (1772–1775) |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 269-272
BO VAHLQUIST,
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07892.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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2. |
FACTOR XIII (FIBRIN STABILISING FACTOR) IN HENOCH‐SCHÖNLEIN'S PURPURA |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 273-277
PER HENRIKSSON,
ULLA HEDNER,
INGA MARIE NILSSON,
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摘要:
Abstract.In 13 out of 17 consecutive children with Henoch‐Schönlein's purpura the factor XIII determined with the dansyl cadaverine method was found to be decreased during the acute phase. The decrease is assumed to be due to a specific degradation by proteolytic enzymes liberated from inflammatory cells, with defective local haemostasis as a result. This assumption is strengthened by the observation that treatment with factor XIII combined with an antifibrinolytic drug controlled life‐threatening gastro‐intestinal bleeding in one of the patients. It would therefore appear that such treatment might offer a new possibility of controlling severe haemorrhages in Henoch‐Schönlein'
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07893.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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3. |
CONGENITAL IMMUNODEFICIENCY AND AGRANULOCYTOSIS (RETICULAR DYSGENESIA) |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 279-283
R. J. HAAS,
D. NIETHAMMER,
S. F. GOLDMANN,
W. HEIT,
U. BIENZLE,
E. KLEIHAUER,
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摘要:
Abstract.A patient is presented who manifested the typical clinical and pathological features of congenital immunodeficiency and agranulocytosis (reticular dysgenesia). Treatment under gnotobiotic conditions enabled the measurement of immunological parameters up to the 17th week of life with the following results: negative skin tests, low response to phytohaemagglutinin, weak response in the mixed leukocyte culture and very few E rosettes. Peripheral lymphocytes and lymphocytes in the lymphatic tissues were markedly decreased. Humoral immunoglobulins and plasma cells in the organs were decreased. The in vitro culture of hemopoietic cells showed a diminished content of myelopoietic progenitor cells (“committed stem cells”). It is concluded that the disease may be primarily a defect of stem cells with regard to differentiation in myelopoiesis or lymphopoie
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07894.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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4. |
CORD BLOOD PORPHYRINSA Quantitative Assay in Newborn Infants |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 285-287
F. HANDA,
S. C. SHARMA,
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摘要:
Abstract.A quantitative assay of free erythrocyte porphyrins was done in umbilical cord blood of 30 newborn babies by a spectrophotometry method. The mean value of free erythrocyte protoporphyrin in umbilical cord blood was found to be 74.58 μg/100 ml packed erythrocytes and that of free erythrocyte coproporphyrin to be 0.77 μg/100 ml packed erythrocytes with a standard deviation of ±29.99 and ±1.48 respectively. Relationship between free erythrocyte protoporphyrin and free erythrocyte coproporphyrin and their correlations with birth weight and sex of the newborn baby were found to be statistically signific
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07895.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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5. |
GENERAL HEALTH SCREENING OF FOUR‐YEAR‐OLDS IN A SWEDISH COUNTY:A Strategy for Improving the Effectiveness and the Costefficiency of the Psychological Screening Program |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 289-295
C. NILSSON,
C. SUNDELIN,
J.‐C. VUILLE,
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摘要:
Abstract.Data presented in a previous paper pointed to the necessity for improving the overall sensitivity of the psychological screening program. The present report indicates possibilities for such an improvement without changing the screening methods. A comparison of the primary data of the true positives, the false positives and all the negatives (non‐referred) revealed the necessity of more stringent referral criteria. It is predicted that the systematic application of these criteria would result in an increase in the rate of true positives form 2.8 to 4.8% of the screened population. In addition a strategy aiming at a reduction of the costs without deteriorating the effectiveness and based on a differential application of the various elements of the screening program is presente
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07896.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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6. |
PHYSICAL HEALTH OF 7‐YEAR‐OLD CHILDRENAn Epidemiological Study of School Entrants and a Comparison with Their Preschool Health |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 297-305
LENNART KÖHLER,
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摘要:
Abstract.At 7 years of age, all 649 7‐year‐old children in a school district underwent a physical examination, a vision screening and an auditory screening. 210 of the children were previously examined in an extensive health control at 4 years of age. The purpose of the present study was to describe the children's health situation and to evaluate the special health control performed at 4 years of age. In 15% of the children, functionally important health problems were found. Visual defects were most common, comprising 7.5%, then came physical health problems such as motor disturbances, obesity, bacteriuria in 6.5%, and hearing defects in 1%. About half of the important health problems were previously known. Children who had passed the special health control at 4 years of age had fewer newly detected important health problems and more previously known ones than other children, which means that many children with above all visual defects but also motor disturbances, bacteriuria and testis retention, were detected and treated earlier than would have happened without the special control at 4 years. It is concluded that the “ordinary” preschool Child Health Services did fulfill their purpose to detect handicapping disorders in an acceptable way; by the introduction of the special health control at 4 years of age, this function was further i
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07897.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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7. |
PHYSICAL MASS EXAMINATIONS IN THE SCHOOL HEALTH SERVICE |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 307-310
LENNART KÖHLER,
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摘要:
Abstract.At 7 years of age, all 649 children in a school district underwent a physical examination, a vision screening and an auditory screening. The purpose of the present study was to analyse the value of the routine physical examination within the school health services. In 15% of the children functionally important health problems were found. Visual defects were most common, comprising 7.5%, then came physical health problems such as motor disturbances, obesity, bacteriuria in 6.5%, and hearing defects in 1%. About half of the important health problems were previously known. Most disorders of importance were detected by the nurse's screening examination and rather few by the doctor's physical examination. It seems advisable to introduce screening procedures in the hands of nurses also for the physical examination. The role of the school physician in the general health surveillance would then be mainly to control and verify specific observations or suspicions of disease or handicap noted by the school nurse. His time and attention could instead be directed towards important tasks, which are now often neglected, e.g. health education, and care of sick and handicapped children in the school setting.
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07898.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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8. |
EXCESSIVE HEPATIC GLYCOGEN STORAGE IN GLUCOSEPHOSPHATE ISOMERASE DEFICIENCY |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 311-315
J.‐P. G. M. VAN BIERVLIET,
G. E. J. STAAL,
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摘要:
Abstract.Excessive amounts of glycogen were found in liver and erythrocytes of a patient suffering from generalized glucosephosphate isomerase deficiency. A low carbohydrate diet, frequent meals and avoidance of peak carbohydrate challenges resulted in a significant decrease of liver volume without affecting the haematological condition. The possible mechanism of these findings are discussed.
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07899.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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9. |
SISOMICIN TREATMENT OF SERIOUS NEONATAL INFECTIONSA Clinical and Pharmacokinetic Study |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 317-322
P. HENRIKSSON,
N. SVENNINGSEN,
G. KAHLMETER,
K. HAEGER,
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摘要:
Abstract.23 infants, 20 of which had verified or clinically highly suspected serious infections in the neonatal period, were treated with a new antibiotic aminoglycoside, sisomicin, i.m. in doses from 2.8 to 6.6 mg/kg/24 h. Clinical cure was obtained in 18 of 20 cases, and marked improvement in one case. Adverse effects were only observed in two infants with tenderness at the injection sites. Serum concentrations and half‐life estimations showed that the concentrations were similar to those obtained for gentamicin, and that half‐life was independent of postnatal age, but highly correlated to the gestational age and to body weight. Consideration should therefore be given to the prolonged half–life of the drug in immature and low birth weight in
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07900.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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10. |
CONGENITAL RICKETSStudy of the Evolution of Secondary Hyperparathyroidism |
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Acta Pædiatrica,
Volume 66,
Issue 3,
1977,
Page 323-327
L. SANN,
L. DAVID,
A. FREDERICH,
M. BOVIER‐LAPIERRE,
J. BOURGEOIS,
M. ROMAND‐MONIER,
M. BETHENOD,
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摘要:
Abstract.A case of congenital rickets of nutritional origin is described in a light‐for‐date premature infant (gestational age 34 weeks, birthweight 1100 g). X‐rays of the long bones showed spread, frayed and cupped metaphyses at birth and at the age of 16 days. Serum calcium was 8.2 mg/100 ml, phosphorus 3.4 mg/100 ml and alkaline phosphatase (A.P.): 323 IU/ml (N≤200) at the age of 3 days. Very high level of serum immunoreactive parathyroid hormone (iPTH) was found at the age of 16 days=295 μlEq/ml (N≤50). Evidence of maternal vitamin D deficiency was demonstrated by low plasma 25‐hydroxycholecalciferol (25‐OH‐CC): 1.0 ng/ml (N: 13.2±4.2) soon after delivery; it was found to be normal (10.2 ng/ml) six months later. Ca infusion (15 mg/kg/3 h) resulted in a marked fall of serum iPTH (280 to 84 μlEq/ml). Administration of vitamin D2(2400 IU/day for 10 days) induced some healing of the metaphyses; A. P. remained elevated (400 IU/ml); plasma 25‐OH‐CC was normal 10.2 ng/ml and serum iPTH was 115 μlEq/ml. When 25‐OH‐CC was given orally for ten days (15 μg/day), plasma 25‐OH‐CC rose to 64.5 ng/ml with a minor change of serum iPTH (94 μlEq/ml); X‐rays of the bones showed osteoporosis. These results suggest a reduced conver
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1977.tb07901.x
出版商:Blackwell Publishing Ltd
年代:1977
数据来源: WILEY
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